科研项目 |
1.VSIG4+巨噬细胞调控缺血再灌注诱导心肌细胞铁死亡的机制研究 国家自然科学基金委员会地区基金项目(82160057)，2022-01至2025-12，34万元，在研，主持 2.心脏干细胞外泌体源circHIPK3调控miR-29a/VEGFA促进内皮祖细胞血管新生机制的研究 国家自然科学基金委员会地区基金项目(81860061)，2019-01至2022-12，35万元，在研，主持 3.缺氧诱导M2型巨噬细胞表达VSIG4 介导心肌梗死后纤维化及血管再生的机制研究 贵州省科技计划项目(黔科合基础-ZK[2021]一般353)，2021.04.01至2024.04.01，10万元，在研，主持 4.循环血清外泌体源circRNA与心肌肥厚的相关性研 究贵州省科技厅联合基金(黔科合LH字[2017]0107), 2017-01 至 2020-12, 7万元, 结题, 主持 |
发表论文 |
1.Yan Wang; Chaofu Li，Ranzun Zhao; Changyin Shen; Weiwei Liu; Zhenglong Wang; Junbo Ge; Bei Shi ;CircUbe3a from M2 macrophage-derived small extracellular vesicles mediates myocardial fibrosis after acute myocardial infarction.Theranostics, 2021, 11(13): 6315-6333(IF:1.556) 2. Yan Wang; Zhimei Qiu; Jinson Yuan; Chaofu Li; Ranzun Zhao; Weiwei Liu; Wenwen Deng; Ning Gu; Wei Zhang; Shan Hu; Zhixun Bai; Bei Shi ; Hypoxia-reoxygenation induces macrophage polarization and causes the release of exosomal miR-29a to mediate cardiomyocyte pyroptosis, In Vitro Cellular & Developmental Biology - Animal, 2021, 36(12): 1-12 SCI( IF:2.416) 3.Yan Wang; Ranzun Zhao; Changyin Shen; Weiwei Liu; Jinson Yuan; Chaofu Li; Wenwen Deng,; Zhenglong Wang; Wei Zhang; Junbo Ge; Bei Shi ; Exosomal CircHIPK3 Released from Hypoxia-Induced Cardiomyocytes Regulates Cardiac Angiogenesis after Myocardial Infarction, Oxidative Medicine and Cellular Longevity, 2020, 4(48): 1-19(IF:6.543) 4.Yan Wang; Ranzun Zhao; Weiwei Liu; Zhenglong Wang; Jidong Rong; Xianping Long; Zhijiang Liu; Junbo Ge; Bei Shi ; Exosomal circHIPK3 Released from Hypoxia-Pretreated Cardiomyocytes Regulates Oxidative Damage in Cardiac Microvascular Endothelial Cells via the miR-29a/IGF-1 Pathway, Oxidative Medicine and Cellular Longevity, 2019,: 1-28( IF:5.076) 5.Yan Wang; Ranzun Zhao; Debin Liu; Wenwen Deng; Guanxue Xu; Weiwei Liu; Jidong Rong; Xianping Long; Junbo Ge; Bei Shi ; Exosomes Derived from miR-214-Enriched Bone Marrow-Derived Mesenchymal Stem Cells Regulate Oxidative Damage in Cardiac Stem Cells by Targeting CaMKII, Oxidative Medicine and Cellular Longevity, 2018, 34(2): 1874-1896 (IF:4.868) 6.王艳,赵然尊,仇治梅等.Mst-1调控缺氧复氧诱导的小鼠心肌细胞自噬及凋亡的机制[J].中华心血管病杂志,2020,48(12):1060-1069. 7.王艳,赵然尊,陈攀科等.微小RNA-214改善高糖诱导的H9c2细胞焦亡的机制探讨[J].中华心血管病杂志,2019(10):820-828. 8.王艳,赵然尊,刘德斌,等. miR-214靶向抑制CaMKⅡ调控H9c2心肌细胞的氧化应激[J]. 第三军医大学学报,2019,41(13):1206-1215. 9.王艳,石蓓,邓文文,等. 过表达微小RNA-21对c-Kit+心脏干细胞增殖、迁移及分化的影响[J]. 中国病理生理杂志,2018,34(6):961-968 |
